Urothelial Carcinoma

Includes cutting-edge methods and protocols
Provides step-by-step detail essential for reproducible results
Contains key notes and implementation advice from the experts

Includes cutting-edge methods and protocols Provides step-by-step detail essential for reproducible results Contains key notes and implementation advice from the experts Includes supplementary material: sn.pub/extras

Inhalt

Analysis of Chromosomal Alterations in Urothelial Carcinoma.- Analysis of Point Mutations in Clinical Samples of Urothelial Carcinoma.- A Versatile Assay for Detection of Aberrant DNA Methylation in Bladder Cancer.- Immunohistochemical Analysis of UC Tissues for Proliferation and Differentiation Markers.- Molecular Subtype Profiling of Urothelial Carcinoma Using a Subtype-Specific Immunohistochemistry Panel.- Defining the Pathways of Urogenital Schistosomiasis-associated Urothelial Carcinogenesis through Transgenic and Bladder Wall Egg Injection Models.- Algorithm for the Automated Evaluation of NAT2 Genotypes.- Detection of APOBEC3 Proteins and Catalytic Activity in Urothelial Carcinoma.- Oxidative Stress in Urothelial Carcinogenesis: Measurements of Protein Carbonylation and Intracellular Production of Reactive Oxygen Species.- Urothelial Carcinoma Stem Cells - current Concepts, Controversies, and Methods.- In Vitro Differentiation and Propagation of Urothelium from Pluripotent Stem Cell Lines.- Spheroid Cultures of Primary Urothelial Cancer Cells: Cancer Tissue-originated Spheroid (CTOS) Method.- The N-butyl-N-4-hydroxybutyl Nitrosamine Mouse Urinary Bladder Cancer Model.- Patient-derived Bladder Cancer Xenografts.- Orthotopic Mouse Models of Urothelial Cancer.- Quantification of microRNAs in Urine-derived Specimens.- Quantitative RNA Analysis from Urine using Real Time PCR.- DNA Methylation Analysis from Body Fluids.- Urinary Protein Markers for the Detection and Prognostication of Urothelial Carcinoma.- Isolation and Characterization of CTCs from Patients with Cancer of a Urothelial Origin.- Epigenetic Treatment Options in Urothelial Carcinoma.- Evaluation of Protein Levels of the Receptor Tyrosine Kinase ErbB3 in Serum.- Targeting the PI3K/AKT/mTOR Pathway in Bladder Cancer.- Visualization and Quantitative Measurement of Frug-induced Platinum Sdducts in the Nuclear DNA of Individual Cells by an Immuno-cytological Sssay. <p