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Suppression and Regulation of Immune Responses

  • Kartonierter Einband
  • 276 Seiten
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This second volume expands upon the previous edition with new research and objectives in immunoregulation and immune tolerance. Ch... Weiterlesen
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This second volume expands upon the previous edition with new research and objectives in immunoregulation and immune tolerance. Chapters cover topics ranging from new molecular and cellular mechanisms of tolerance; generation and characterization of mice regulatory macrophages; recent advances in the treatment of immune-mediated inflammatory disorders; and novel mechanisms and therapeutic perspectives on food allergies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Suppression and Regulation of Immune Responses: Methods and Protocols, Volume II is a great resource for current research and inspiration for new studies in immune tolerance.

Includes cutting-edge methods and protocols

Provides step-by-step detail essential for reproducible results

Contains key notes and implementation advice from the experts


Part I: New Molecules and Cellular Mechanisms of Immunoregulation

1) HLA-G as an Inhibitor of Immune Responses
Aifen Lin and Wei Hua Yan

2) New Molecular and Cellular Mechanisms of Tolerance: Tolerogenic Actions of IL-2
Louis Pérol and Elianne Piaggio

3) Expansion of Regulatory T Cells In Vitro and In Vivo by IL-33
Benjamin M. Matta and Hth R. Turnquist

4) Standardization, Evaluation, and Area-Under-Curve Analysis of Human and Murine Treg Suppressive Function
Tatiana Akimova, Matthew H. Levine, Ulf H. Beier, and Wayne W. Hancock

5) Characterization and Immunoregulatory Properties of Innate Pro-B-Cell Progenitors
Flora Zavala, Sarantis Korniotis, and Ruddy Montandon

6) Generation and Characterization of Mice Regulatory Macrophages
Laura Carretero-Iglesia, Marcelo Hill, and Marie-Cristina Cuturi

7) Generation and Expansion of T Helper 17 Lymphocytes Ex-Vivo
Darya Alizadeh and Nicolas Larmonier

Part II: Animal Models of Immunoregulation

8) Autoimmune Diabetes: An Overview of Experimental Models and Novel Therapeutics
Sylvaine You and Lucienne Chatenoud

9) Recent Advances in the Treatment of Immune-Mediated Inflammatory Disorders
Sander W. Tas and Dominique L. P. Baeten

10) Application of Humanized Mice in Immunological Research
Wenwei Tu and Jian Zheng

11) Humanized Mice as Pre-Clinical Models in Transplantation
N. Safina, P. Becker, T. Vaikunthanathan, F. Xiao, R. Lechler, Giovanna Lombardi

12) Dextran Sulfate Sodium (DSS)-Induced Acute Colitis in the Rat
Jérôme C. Martin, Gaëlle Bériou, and Régis Josien

13) Corneal Immunosuppressive Mechanisms, Anterior Chamber-Associated Immune Deviation (ACAID) and their Role in Allograft Rejection
Oliver Treacy, Gerry Fahy, Thomas Ritter, and Lisa O'Flynn

14) Food Allergies: Novel Mechanisms and Therapeutic Perspectives
Margherita Di Costanzo, Lorella Paparo, Linda Cosenza, Carmen Di Scala, Rita Nocerino, Rosita Aitoro, and Roberto Berni Canani

Part III Immunomonitoring and Biomarkers

15) Standardized Multi-Color Flow Cytometry and Computational Biomarker Discovery
Stephan Schlickeiser, Mathias Streitz, and Birgit Sawitzki

16) The Aryl Hydrocarbon Receptor in Immunity Tools and Potential
Charlotte Esser


Titel: Suppression and Regulation of Immune Responses
Untertitel: Methods and Protocols, Volume II
EAN: 9781493949892
ISBN: 1493949896
Format: Kartonierter Einband
Herausgeber: Springer New York
Genre: Medizin
Anzahl Seiten: 276
Gewicht: 525g
Größe: H254mm x B178mm x T14mm
Jahr: 2016
Auflage: Softcover reprint of the original 1st ed. 2016

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