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Small Molecules in Oncology

  • Kartonierter Einband
  • 436 Seiten
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Extensive research into the molecular mechanisms of cancer has heralded a new age of targeted therapy. The field of personalized c... Weiterlesen
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Beschreibung

Extensive research into the molecular mechanisms of cancer has heralded a new age of targeted therapy. The field of personalized cancer therapy is now growing rapidly, and the progress being made will result in significant changes in the treatment algorithms for cancer patients. Numerous novel targets that are crucial for the survival of cancer cells can be attacked by small molecules such as protein tyrosine kinase inhibitors. This book, written by acknowledged experts, discusses in detail the most recent developments in targeted cancer therapy using small molecules. A wide range of small molecules is covered, including, in addition to tyrosine kinase inhibitors, mTOR, proteasome, and multikinase inhibitors, among others. For each molecule, aspects such as chemical structure, mechanism of action, drug targets, drug interactions, preclinical studies, clinical trials, treatment applications, and toxicity are discussed.

Detailed coverage of the most recent developments in targeted cancer therapy using small molecules

Full discussion of preclinical studies, clinical trials, and treatment applications

Written by acknowledged experts



Inhalt
Imatinib Mesylate.- Erlotinib.- Axitinib (AG-013736).- Lapatinib.- Sorafenib.- Sunitinib.- Dasatinib.- Nilotinib.- Bosutinib.- Decitabine.- Azacytidine/Azacitidine.- Bortezomib.- Temsirolimus.- Danusertib.- Vismodegib.- Everolimus.- Vemurafenib.- Vandetanib.- Trametinib.- Dabrafenib.- Ponatinib.- Regorafenib.- Cabozantinib.- Revlimid.- Ibrutinib.- Qizartinib.- Ruxolitinib.- Carfilzomib.- Afitinib.

Produktinformationen

Titel: Small Molecules in Oncology
Editor:
EAN: 9783662519257
ISBN: 3662519259
Format: Kartonierter Einband
Herausgeber: Springer Berlin Heidelberg
Genre: Medizin
Anzahl Seiten: 436
Gewicht: 657g
Größe: H235mm x B155mm x T23mm
Jahr: 2016
Untertitel: Englisch
Auflage: Softcover reprint of the original 2nd ed. 2014