Proteins: Structure, Function, and Engineering

Here, researchers review the latest breakthroughs in protein research. Their contributions explore emerging principles and techniques and survey important classes of proteins that will play key roles in the field's future. Articles examine the possibility of a Boltzman-like distribution in protein substructures, the new technique of Raman spectroscopy, and compact intermediate states of protein folding. This well-illustrated volume also features coverage of proteins that bind nucleic acids.

Inhalt
1 Boltzmann-like Statistics of Protein Architectures: Origins and Consequences.- 2 Compact Intermediate States in Protein Folding.- 3 Raman Spectroscopy of Proteins and Their Assemblies.- 4 Fluorescence Spectroscopic Studies of Proteins.- 5 Pyrene Excimer Fluorescence as a Probe of Protein Conformational Change.- 6 Differential Scanning Calorimetry of Proteins.- 7 Affinity Labeling and Related Approaches to Targeting Specific Enzyme Sites.- 8 Tryptophan Synthase: Structure, Function, and Protein Engineering.- 9 Structure and Function in the Tubulin Dimer and the Role of the Acidic Carboxyl Terminus.- 10 Role of Allosteric Changes in Cyclic AMP Receptor Protein Function.- 11 A Family of RNA-Binding Enzymes: The Aminoacyl-tRNA Synthetases.- 12 Functions and Structures of Ribonuclease H Enzymes.