Willkommen, schön sind Sie da!
Logo Ex Libris

Macromolecular Drug Delivery

  • Kartonierter Einband
  • 220 Seiten
(0) Erste Bewertung abgeben
Bewertungen
(0)
(0)
(0)
(0)
(0)
Alle Bewertungen ansehen
Macromolecular drugs could become new therapeutics for several major disorders, including cancer and cardiovascular disease. This ... Weiterlesen
20%
165.00 CHF 132.00
Print on Demand - Auslieferung erfolgt in der Regel innert 4 bis 6 Wochen.
Bestellung & Lieferung in eine Filiale möglich

Beschreibung

Macromolecular drugs could become new therapeutics for several major disorders, including cancer and cardiovascular disease. This incredible potential is explored in a volume which gives a wide-ranging overview of contemporary methods used in the field.


Macromolecular drugs hold the promise of becoming new therapeutics for several major disorders, including cancer and cardiovascular disease. This incredible potential is explored in Macromolecular Drug Delivery, a volume which gives a wide-ranging overview of contemporary methods used in the field, and which addresses the limitations presented by a lack of safe and efficient drug delivery strategies. Chapters offer information on both in vitro and in vivo methods of macromolecular delivery, thus appealing to a broad scientific audience. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.

Comprehensive and cutting-edge, Macromolecular Drug Delivery offers a platform for interdisciplinary collaboration, which should provide opportunities for new discoveries at the interface between disciplines. Ultimately, this cooperation will lead to the use of macromolecular drugs as novel diagnostic tools and, even more importantly, as a means to revolutionize the way we view and treat diseases.



Provides cutting edge methods for in vitro and in vivo studies of nucleic acid based drugs

Presents detailed protocols for preparation of non-viral drug delivery vehicles and artificial membrane models

Includes a comprehensive description of retrieval of internalizing antibodies from phage display libraries

Gives step-by-step methods for in vitro and in vivo studies of macromolecular delivery across biological barriers



Inhalt
Macromolecular Drug Delivery Dr. Mattias Belting, ed. Table of Contents Preface Contributors Developments in Macromolecular Drug Delivery; Review Chapter Mattias Belting and Anders Wittrup Synthetic vs. Natural/Biodegradable Polymers for Delivery of shRNA Based Cancer Therapies; Review chapter John S. Vorhies and John J. Nemunaitis siRNA and DNA Transfer to Cultured Cells Bagavathi Gopalakrishnan and Jon Wolff Poly(ß-amino esters): Procedures for Synthesis and Gene Delivery Jordan J. Green, Gregory T. Zugates, Robert Langer, and Daniel G. Anderson Systemic Delivery and Preclinical Evaluation of Nanoparticles Containing Antisense Oligonucleotides and siRNAs Chuanbo Zhang, Joseph T. Newsome, Rajshree Mewani, Jin Pei, Prafulla C. Gokhale, and Usha N. Kasid Peptide-based Delivery of Steric-block PNA Oligonucleotides Saïd Abes, Gabriela D. Ivanova, Rachida Abes, Andrey A. Arzumanov, Donna Williams, David Owen, Bernard Lebleu and Michael J. Gait Characterizing Peptide Mediated DNA Internalization in Human Cancer Cells Anders Wittrup and Mattias Belting Selection and Characterization of Antibodies from Phage Display Libraries against Internalizing Membrane Antigens Johan Fransson and Carl A. K. Borrebaeck Artificial Membrane Models for the Study of Macromolecular Delivery Lena Mäler and Astrid Gräslund Enhanced Delivery of Macromolecules into Cells by Electroendocytosis Alexander Barbul, Yulia Antov, Yosef Rosenberg and Rafi Korenstein In Vitro Systems for Studying Epithelial Transport of Macromolecules Nicole Daum, Andrea Neumeyer, BirgitWahl, Michael Bur, Claus-Michael Lehr Preparation of Macromolecule-containing Dry Powders for Pulmonary Delivery Kelly S. Kraft and Marshall Grant Macromolecular Delivery Across the Blood-Brain Barrier Kullervo Hynynen Positron Emission Tomography (PET) and Macromolecular Delivery In Vivo Ludwig G. Strauss and Antonia Dimitrakopoulou-Strauss

Produktinformationen

Titel: Macromolecular Drug Delivery
Untertitel: Methods and Protocols
Editor:
EAN: 9781627039666
ISBN: 162703966X
Format: Kartonierter Einband
Herausgeber: Humana Press
Genre: Medizin
Anzahl Seiten: 220
Gewicht: 341g
Größe: H235mm x B155mm x T12mm
Jahr: 2014
Auflage: 2009

Weitere Produkte aus der Reihe "Methods in Molecular Biology"