Beschreibung

This book presents practical information on the clinical applications of short pulse laser systems and the techniques for optimizing these applications in a manner that will be relevant to a broad audience, including engineering and medical students as well as researchers, clinicians, and technicians. Short pulse laser systems are useful for both subsurface tissue imaging and laser induced thermal therapy (LITT), which hold great promise in cancer diagnostics and treatment. Such laser systems may be used alone or in combination with optically active nanoparticles specifically administered to the tissues of interest for enhanced contrast in imaging and precise heating during LITT. Mathematical and computational models of short pulse laser-tissue interactions that consider the transient radiative transport equation coupled with a bio-heat equation considering the initial transients of laser heating were developed to analyze the laser-tissue interaction during imaging and therapy. Experiments were first performed to characterize the tissue optical properties needed to optimize the dose for thermal therapy. Experiments were then performed on animal models to characterize the heat affected zone for LITT. The experimental measurements were also validated using the computational models.

Analyzes several clinically relevant uses of short pulse laser systems, including the newest ones used in cancer diagnostics and treatment

Concisely presents key points regarding the results of lab experiments and computer simulations in order to demonstrate the fundamental science behind the applications of this technology

Demonstrates how to improve the safety and efficacy of this technology through enhanced contrast in imaging and precise heating

Autorentext

Inhalt
Introduction.- Short Pulse Laser Imaging.- Short Pulse Laser Based Thermal Therapy.- Use of Nanoparticles to Optimize Short Pulse Laser Based Biomedical Applications.

Produktinformationen

Titel:	Short Pulse Laser Systems for Biomedical Applications
Autor:	Kunal Mitra   Stephanie Miller
EAN:	9783319542522
ISBN:	978-3-319-54252-2
Format:	Kartonierter Einband
Herausgeber:	Springer, Berlin
Genre:	Medizin
Anzahl Seiten:	49
Gewicht:	113g
Größe:	H5mm x B237mm x T169mm
Jahr:	2017
Untertitel:	Englisch
Auflage:	1st ed. 2017