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Ketosis in Domestic Animals

  • Fester Einband
  • 72 Seiten
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Excerpt from Ketosis in Domestic Animals: Clinical and Experimental ObservationsChemistry. That the chief source of ketone bodies... Weiterlesen
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Excerpt from Ketosis in Domestic Animals: Clinical and Experimental Observations

Chemistry. That the chief source of ketone bodies is fat seems to be well established.47 It is much less certain, however, just how these substances are produced from fat in the liver. Oxidation of fat in viva apparently begins with hydrolysis of the fat molecule to glycerol and fatty acid. Then further oxidation of these components occurs. Glycerol, which represents about 10 percent of the fat mole cule, like glucose, probably gives rise to glycogen in the liver.7 Bio chemists have found great difficulty in following the changes that occur during oxidation of the fatty acid fraction. A theory presented by Knoop in 1904, however, provides a clue to a fundamental reaction which may take place during intermediate fat metabolism. Kn00p's theory is that in each step in the breakdown of fatty acids that contain an even number of carbon atoms (those present in natural fats) oxidation occurs at the carbon atom in the Beta-position to the carboxyl group. By this process two carbon atoms are Split off in each step until the 4-carbon atom stage is reached. At this stage, acetoacetic acid is one of the products. This acid is then converted to acetic acid, which undergoes further changes to carbon dioxide and water.

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Titel: Ketosis in Domestic Animals
Untertitel: Clinical and Experimental Observations (Classic Reprint)
EAN: 9780331608212
ISBN: 0331608219
Format: Fester Einband
Genre: Medizin
Anzahl Seiten: 72
Gewicht: 257g
Größe: H229mm x B152mm x T8mm
Jahr: 2017



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