Genes and Proteins Underlying Microbial Urinary Tract Virulence

Proceedings of the FEMS Symposium on Genes and Proteins Underlying Microbial Urinary Tract Virulence: Basic Aspects and Applications, held September 16-19, 1999, in Pécs, Hungary.
Urinary tract infections are among the most frequent diseases caused by microbial pathogens. In this volume, researchers, clinical microbiologists and clinicians exchange the latest ideas covering four major aspects of this important topic:

• Genetic information, synthesis and assembly of virulence factors in urinary pathogens;
• Regulation of genes involved in the phenotypic appearance of virulence;
• Host-parasite interactions determining the process and outcome of the infection;
• Possible applications of the above aspects in diagnosis, therapy and prevention.

Inhalt
Keynote Lectures.- Urinary Tract Infection: From Basic Science to Clinical Application.- Innate Defences and Resistance to Gram Negative Mucosal Infection.- Genetic Imformation, Synthesis, Assembly, and Activation Processes in Virulence Mechanisms.- Pathogenicity Islands of Uropathogence E. Coli and Evolution of Virulence.- Iron Transport In Escherichia coli.- The Cytotoxic Necrotizing Factor 1 (CNF1) from Uropathogenic Escherichia coli.- Genetic Characterization of the Uropathogenic E. coli Strain 536 A Subtractive Hybridization Analysis.- Analysis of the Hemolysin Determinants of the Uropathogenic Escherichia coli Strain 536.- Functional Variability of Type 1 Fimbriae of Escherichia coli.- HPI of High-Virulent Yersinia is Found in E. coli Strains Causing Urinary Tract Infection.- Aggregation Substance of Enterococcus Faecalis: A Multifunctional Adhesin.- Regulation and Expression of Virulence Genes.- A Role for the ?s Subunit of RNA Polymerase in the Regulation of Bacterial Virulence.- Transcriptional Organisation and Regulation of E. coli Group 2 Capsule Expression.- Molecular Basis of Catheter Associated Infections by Staphylococci.- Control Mechanisms in the Pap-pili System.- Transcriptional Analysis of the Sfa and Pap Determinants of Uropathogenic Escherichia Coli Strains.- Structural and Functional Studies of the Fimbrial Adhesin Gene Regulator papB from Uropathogenic Escherichia coli.- Interaction of the Nucleoid-Associated Proteins HAA and H-NS to Modulated Expression of the Hemolysin Operon in Escherichia coli.- Use of the OmpS-display-system to Localize Thereceptor-bindingregion in the PapG Adhesin of Uropathogenic Escherichia coli.- The Role of the Airs Two-component System in Uropathogenic Escherichia Coli.- Examination of Regulatory Cross-talk Betweenthe Decay Accelerating Factor-binding Fimbrial/Afimbrial Adhesins and Type I Fimbriae.- Modulation of the Polysaccharide Intercellular Adhesin (PIA) Expression in Biofilm Forming Staphylococcus Epidermidis.- Induction of Staphylococcus Epidermidis Biofilm Formation by Environmental Factors: The Possible Involvement of the Alternative Transcription Factor SigB.- Expression of Virulence Genes in Candida Albicans.- Effect of Spontaneous and Induced Mutations on Outer Membrane Proteins and Lipopolysaccharides of Proteus Penneri Strain 357.- Host-parasite Interactions.- Role of Bacterial Lectins in Urinary Tract Infections.- Adherence of Enteric Bacteria Onto the Mammalian Extracellular Matrix.- Interrelationship Between Virulence Properties of Uropathogenic E. coli and Blood Group Phenotype of Patients with Chronic Urinary Tract Infection.- Glycolipid Receptors of F1C Fimbrial Adhesin of Uropathogenic Escherichia coli.- Thin Aggregative Fimbriae on Urinary Escherichia coli Isolates.- Type 1 Plili of Citrobacter freundii Mediate Invasion into Host Cells.- Serotypes, Siderophore Synthesis, and Serum Resistance of Uropathogenic Klebsiella Isolates.- Epitope Specificity of Polyclonal Rabbit Antisera Against Proteus Vulgaris O-Antigens.- Virulence Factors of Eescherichia coli Isolated from Urine of Diabetic Women with Asymptomatic Bacteriuria.- Cytokine Secretion is Impaired in Women with Diabetes Mellitus.- Characterisation and Adherence Mechanisms of Escherichia coli Strains Causing Infections in Patients with a Reconstructed Bladder.- Immunodominant Proteins in Human Sepsis Caused by Methicillin Resistant Staphylococcus aureus.- Applications: Diagnosis, Therapy and Prevention.- Modern Concept of Antibiotic Therapy of Urinary Tractinfections.- The Role of Anaerobic Bacteria in Prostatitis.- Urinary Tract Infection in Dogs.- Detection of Virulence Factors in Uropathogenic Escherichia Coli Isolated from Humans, Dogs and Cats in Portugal.- Asymptomatic Bacteriuria can be Considered a Diabetic Complication in Women with Diabetes Mellitus.- Determination of Genetic Diversity of Proteus Penneri Strains Using Rep-PCR.- Use of Randomly Amplified Polymorphic DNA (RAPD) Analysis for Identification of Proteuspenneri.- Overview on the Clinical Studies with Urostim Immunostimulator Against Urogenital Infections.- Porcine Postweaning Diarrhea Isolates of Escherichia Coli with Uropathogenic Characters.- Virulence Markers of Human Uropathogenic Escherichia coli Strains Isolated in Hungary.- New Serogroups of the Genus Proteus Consisting of Proteus Penneri Strains only.- The Role of Chlamydia trachomatis in Asymptomatic and Symptomatic Urogential Infections.