Informationen zum Autor Edited by Gary S. Hoffman MD, MS Professor of Medicine Department of Rheumatic and Immunologic Diseases Center for Vasculitis Care and Research Cleveland Clinic Lerner College of Medicine Cleveland, OH, USA Cornelia M. Weyand MD, PhD Professor of Medicine Stanford University School of Medicine Stanford, CA, USA Carol A. Langford MD, MHS Director, Center for Vasculitis Care and Research Department of Rheumatic and Immunologic Diseases Cleveland Clinic Lerner College of Medicine Cleveland, OH, USA Jörg J. Goronzy MD, PhD Professor of Medicine Stanford University School of Medicine Stanford, CA, USA Klappentext In recent years, considerable progress has been made in understanding the vasculitic diseases, largely due to the introduction of effective treatments for diseases that were once uniformly fatal, the conduct of structured clinical studies, and advances in immunology and molecular biology. Despite these achievements, the vasculitic diseases continue to be associated with morbidity and mortality from chronic organ damage, relapses, and the side effects of treatment. Investigations into the mechanisms of vascular inflammation may lead to a better comprehension of the pathogenesis of vasculitic diseases and to treatment that is more effective and less toxic. These areas of promising research, together with current knowledge about the vasculitic diseases, are extensively examined in this new edition, which is designed to provide a comprehensive overview of the science and clinical consequences of vascular inflammation in health and disease. Zusammenfassung In recent years, considerable progress has been made in understanding the vasculitic diseases, largely due to the introduction of effective treatments for diseases that were once uniformly fatal, the conduct of structured clinical studies, and advances in immunology and molecular biology. Inhaltsverzeichnis List of ContributorsPrefaceSection I. Biology of Blood Vessels and Mechanisms of Vascular Inflammation1 Vascular DevelopmentDomenico Ribatti and Enrico Crivellato2 Vascular RepairChristian Troidl, Kerstin Troidl, Georg Jung, Thomas Schmitz-Rixen and Wolfgang Schaper3 Leukocyte TraffickingBraedon McDonald and Paul Kubes4 Dendritic Cells and Vascular InflammationCornelia M. Weyand5 T Cells and Vascular InflammationJörg J. Goronzy6 Autoantibodies and Vascular InflammationA.Rutgers, J.S.F. Sanders, J.W. Cohen Tervaert, C.G.M. Kallenberg7 Neutrophils and Vascular InflammationMatthew David Morgan and Caroline OS Savage8 Cytokines and Vascular InflammationMaria C Cid, Marc Corbera-Bellalta, Ester Planas-Rigol, Ester Lozano, Georgina Espígol-Frigolé, Ana García-Martínez, José Hernández-Rodríguez, Marta Segarra9 Oxidative Stress and Vascular InflammationDavid G. Harrison10 Hemostasis and Vascular InflammationLawrence Leung and John Morser11 Animal Models of VasculitisMasato Nose12 Arteries, Smooth Muscle Cells, and Genetic Causes of Thoracic Aortic AneurysmsAmy J. Reid and Dianna M. Milewicz13 Innate Immunity in AtherosclerosisShuang Chen, Prediman K. Shah and Moshe Arditi14 Adaptive Immunity in AtherosclerosisJan NilssonSection II. Primary Autoimmune Vascular Diseases15 Historical Perspectives VasculitisEric L. Matteson16 Approach to the Differential Diagnosis of VasculitisEamonn S. Molloy and Carol A. Langford17 Imaging of medium and large vessels (CT/PET/MR)Thorsten Alexander Bley18 Kawasaki diseaseRae S.M. Yeung19 Henoch-Schonlein PurpuraPhilip J. Hashkes and Alexandra Villa-Forte20 Polyarteritis NodosaEli M. Miloslavsky and John H. Stone21 Microscopic polyangiitisCoen Stegeman22 Granulomatosis with Polyangiitis (Wegener's Granulomatosis)Gary S. Hoffman, Carol A. Langford and Ulrich Specks23 Churg-Strauss Syndrome (Eosinophilic Granulomatosis with Polyangiitis, EGPA)Christian...

Autorentext

**Edited by

Gary S. Hoffman MD, MS
Professor of Medicine Department of Rheumatic and Immunologic Diseases Center for Vasculitis Care and Research Cleveland Clinic Lerner College of Medicine Cleveland, OH, USA Cornelia M. Weyand MD, PhD
Professor of Medicine Stanford University School of Medicine Stanford, CA, USA Carol A. Langford MD, MHS
Director, Center for Vasculitis Care and Research Department of Rheumatic and Immunologic Diseases Cleveland Clinic Lerner College of Medicine Cleveland, OH, USA Jörg J. Goronzy MD, PhD
Professor of Medicine Stanford University School of Medicine Stanford, CA, USA

Klappentext

In recent years, considerable progress has been made in understanding the vasculitic diseases, largely due to the introduction of effective treatments for diseases that were once uniformly fatal, the conduct of structured clinical studies, and advances in immunology and molecular biology. Despite these achievements, the vasculitic diseases continue to be associated with morbidity and mortality from chronic organ damage, relapses, and the side effects of treatment. Investigations into the mechanisms of vascular inflammation may lead to a better comprehension of the pathogenesis of vasculitic diseases and to treatment that is more effective and less toxic. These areas of promising research, together with current knowledge about the vasculitic diseases, are extensively examined in this new edition, which is designed to provide a comprehensive overview of the science and clinical consequences of vascular inflammation in health and disease.

Inhalt

List of Contributors Preface Section I. Biology of Blood Vessels and Mechanisms of Vascular Inflammation 1 Vascular Development Domenico Ribatti and Enrico Crivellato 2 Vascular Repair Christian Troidl, Kerstin Troidl, Georg Jung, Thomas Schmitz-Rixen and Wolfgang Schaper 3 Leukocyte Trafficking Braedon McDonald and Paul Kubes 4 Dendritic Cells and Vascular Inflammation Cornelia M. Weyand 5 T Cells and Vascular Inflammation Jörg J. Goronzy 6 Autoantibodies and Vascular Inflammation A.Rutgers, J.S.F. Sanders, J.W. Cohen Tervaert, C.G.M. Kallenberg 7 Neutrophils and Vascular Inflammation Matthew David Morgan and Caroline OS Savage 8 Cytokines and Vascular Inflammation Maria C Cid, Marc Corbera-Bellalta, Ester Planas-Rigol, Ester Lozano, Georgina Espígol-Frigolé, Ana García-Martínez, José Hernández-Rodríguez, Marta Segarra 9 Oxidative Stress and Vascular Inflammation David G. Harrison 10 Hemostasis and Vascular Inflammation Lawrence Leung and John Morser 11 Animal Models of Vasculitis Masato Nose 12 Arteries, Smooth Muscle Cells, and Genetic Causes of Thoracic Aortic Aneurysms Amy J. Reid and Dianna M. Milewicz 13 Innate Immunity in Atherosclerosis Shuang Chen, Prediman K. Shah and Moshe Arditi 14 Adaptive Immunity in Atherosclerosis Jan Nilsson Section II. Primary Autoimmune Vascular Diseases 15 Historical Perspectives Vasculitis Eric L. Matteson 16 Approach to the Differential Diagnosis of Vasculitis Eamonn S. Molloy and Carol A. Langford 17 Imaging of medium and large vessels (CT/PET/MR) Thorsten Alexander Bley 18 Kawasaki disease Rae S.M. Yeung 19 Henoch-Schonlein Purpura Philip J. Hashkes and Alexandra Villa-Forte 20 Polyarteritis Nodosa Eli M. Miloslavsky and John H. Stone 21 Microscopic polyangiitis Coen Stegeman 22 Granulomatosis with Polyangiitis (Wegener's Granulomatosis) Gary S. Hoffman, Carol A. Langford and Ulrich Specks 23 Churg-Strauss Syndrome (Eosinophilic Granulomatosis with Polyangiitis, EGPA) Christian Pagnoux and Loïc Guillevin 24 Giant cell arteritis Cornelia M. Weyand and Jörg J. Goronzy 25 Takayasu's arteritis Kathleen Maksimowicz-McKinnon and Gary S. Hoffman 26 Behçet's Syndrome Yusuf Yazici, Ismail Simsek and Hasan Yazici 27 Cogan's Syndrome Rex M. McCallum and E. William St. Clair 28 Idiopathic cryoglobulinemic vasculitides Benjamin Terrier and Patrice Cacoub 29 Primary central nervous system vasculitis Rula A. Hajj-Ali and Leonard H. Calabrese 30 Single organ vasculitis José Hernández-Rodríguez and Gary S. Hoffman 31 Primary cutaneous vasculiti…