Cardiac Markers

Cardiac Markers is a comprehensive, up-to-date summary of clinical information on serum cardiac markers for coronary artery disease. This book reviews in detail the biochemistry, clinical significance, and analytical measurements for each marker, as well as the advantages and limitations of existing and proposed markers. Comprehensive descriptions of therapeutic approaches to manage patients are presented. Also included are up-to-date listings of primary references and commercial methodologies, the latest data on the pathophysiology of unstable angina, and a discussion of the new emergency-room chest pain centers. Anyone who needs to know how to examine, diagnose, treat, and manage patients with acute chest pain and heart attacks will find this book indispensable.

Inhalt
I Clinical Aspects.- 1 Introduction to Coronary Artery Disease (CAD) and Biochemical Markers.- 2 Pathophysiology of Acute Coronary Syndromes.- 3 Pathophysiology and Treatment of Acute Myocardial Ischemia and Infarction.- 4 Markers of Myocardial Injury in the Evaluation of the Emergency Department Patient with Chest Pain.- 5 Ultrastructure of the Striated Muscle Cell.- II Cytoplasmic Markers.- 6 Myoglobin and Carbonic Anhydrase III.- 7 Creatine Kinase, Isoenzymes, and Variants.- 8 CK-MB Activity Assays.- 9 CK-MB Measurements by Immunoassay.- 10 CK Isoforms.- 11 Lactate Dehydrogenase and Its Isoenzymes.- III Structural Markers.- 12 Biochemistry and Molecular Biology of Troponins I and T.- 13 Cardiac Troponin T as a Marker of Myocardial Injury.- 14 Cardiac Troponin I.- 15 Myosin Light and Heavy Chains.- IV Future Assay and Format.- 16 Point-of-Care Testing for Cardiac Markers.- 17 New Biochemical Markers for Heart Diseases.