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Cancer and IgE

  • Kartonierter Einband
  • 300 Seiten
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This is a comprehensive volume about the evolving new field AllergoOncology. The book, the first of its class, attempts to explore... Weiterlesen
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Beschreibung

This is a comprehensive volume about the evolving new field AllergoOncology. The book, the first of its class, attempts to explore step by step the interesting questions emerging from this novel science field.

Erika Jensen-Jarolim and Manuel L. Penichet 1. 1 Background Infectious diseases, being the major burden in the history of mankind worldwide th until the beginning of the 20 century, were important triggers in the understanding of immunological mechanisms. In contrast to infectious diseases, reports of all- gies and cancers were less common, but increased tremendously within the last century. Based on the US mortality data of the National Center for Health Statistics, Centers for Disease Control and Prevention 2009, a recent report from the American Cancer Society indicated that the number of cancer deaths increased approximately from 100,000 to 550,000 per year between 1930 and 2006, paralleling the increase of the total population during this period. Leading causes of death from cancer are lung and bronchus cancer, in men prostate cancer, and in women breast c- cer [1, 2]. Normalization to population size shows that the cancer death rate for most malignancies has been generally stable, although the mortality rate of certain malignancies, such as lung and bronchus cancer, has increased over the last 50 years [1-3]. In allergy, the situation is less clear, because for the time period around the turn of th the 19 century, only imprecise information is available. However, within the last 30 years the incidences of allergies has doubled not only in industrial countries, but in developing countries as well [4].

Inhalt

Chapter 1
Introduction
Erika Jensen-Jarolim and Manuel L. Penichet

Chapter 2
The Biology of IgE: Molecular Mechanism Restraining Potentially Dangerous High Serum IgE Titres in Vivo
Gernot Achatz, Gertrude Achatz-Straussberger, Stefan Feichtner, Sebastian Koenigsberger, Stefan Lenz, Doris Peckl-Schmid, Nadja Zaborsky, and Marinus Lamers

Chapter 3
The Biology of IgE: the Generation of High Affinity IgE Antibodies.
Maria A. Curotto de Lafaille and Juan J. Lafaille

Chapter 4
Epidemiological evidence: IgE, Atopy, and Solid Tumors
Michelle C. Turner

Chapter 5
Epidemiological Evidence: IgE, Allergies, and Hematopoietic Malignancies
Otoniel Martínez-Maza, Alan Duane Moreno, and Wendy Cozen

Chapter 6
Mast Cells in Allergy and Tumor Disease
Anna Wasiuk, Victor C. de Vries, Elizabeth C. Nowak, and Randolph J. Noelle

Chapter 7
The IgE Antibody and Its Use in Cancer Immunotherapy
Tracy R. Daniels, José A. Rodríguez, Elizabeth Ortiz-Sánchez, Gustavo Helguera, and Manuel L. Penichet

Chapter 8
IgE Interacts with Potent Effector Cells Against Tumors: ADCC and ADCP
Sophia N. Karagiannis, Frank O. Nestle, and Hannah J. Gould

Chapter 9
IgE as Adjuvant in Tumor Vaccination
Elisa A. Nigro, Antonio G. Siccardi, and Luca Vangelista

Chapter 10
The Targets of IgE: Allergen-Associated and Tumor-Associated Molecular Patterns (AAMPs and TAMPs)
Erika Jensen-Jarolim, Diana Mechtcheriakova, Isabella Pali-Schoell

Chapter 11
The Role of Th2-Mediated Anti-Tumor Immunity in Tumor Surveillance and Clearance
Ljubov Simson, Julia I. Ellyard, and Christopher R. Parish

Produktinformationen

Titel: Cancer and IgE
Untertitel: Introducing the Concept of AllergoOncology
Editor:
EAN: 9781627038522
ISBN: 1627038523
Format: Kartonierter Einband
Genre: Medizin
Anzahl Seiten: 300
Gewicht: 456g
Größe: H235mm x B155mm x T16mm
Jahr: 2014
Auflage: 2010

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