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Calcium Signaling, 2 Teile

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  • 1110 Seiten
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This book covers topics ranging from fundamental aspects of calcium signaling to its clinical implications, in a thoughtful and co... Weiterlesen
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This book covers topics ranging from fundamental aspects of calcium signaling to its clinical implications, in a thoughtful and comprehensive way. Includes discussion of calcium signaling in different mammalian cells, oocytes, Zebrafishes and even in plants.

This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative.
The chapter "Calcium Signaling: From Basic to Bedside" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.



Calcium signaling: from basics to bedside

Md. Shahidul Islam


Measuring Ca2+ in living cells

Joseph Bruton, Arthur J Cheng & Håkan Westerblad


High-throughput fluorescence assays for Ion Channels and GPCRs

Irina Vetter, David Carter, John Bassett, Jennifer R. Deuis, Bryan Tay, Sina Jami, Samuel D. Robinson.


Imaging Native Calcium Currents in Brain Slices

Karima Ait Ouares, Nadia Jaafari, Nicola Kuczewski and Marco Canepari


Molecular diversity of plasma membrane Ca2+ transporting ATPases: their function under normal and pathological conditions.


Luca Hegeds, Boglárka Zámbó, Katalin Pászty, Rita Padányi, Karolina Varga, John T. Penniston, Ágnes Enyedi


A role for SERCA pumps in the neurobiology of neuropsychiatric and neurodegenerative disorders

Aikaterini Britzolaki, Joseph Saurine, Benjamin Klocke, Pothitos M. Pitychoutis


Cytoplasmic Calcium Buffering: An Integrative Crosstalk

Juan A. Gilabert

An update on calcium binding proteins

Jacobo Elíes, Matilde Yáñez, Thiago M.C. Pereira, José GilLongo, David A. MacDougall &

Manuel  CamposToimil

Phospholipase C

Colin A. Bill and Charlotte M. Vines


New insights in the IP3 receptor and its regulation



Expression of the inositol 1,4,5-trisphosphate receptor and the ryanodine receptor Ca2+-release channels in the beta-cells and alpha- cells of the human islets of Langerhans

Fabian Nordenskjöld, Björn Andersson, Md. Shahidul Islam.


Evolution of Excitation-Contraction Coupling

John J. Mackrill and Holly A. Shiels


Molecular Insights into Calcium Dependent Regulation of Ryanodine Receptor Calcium Release Channels

Naohiro Yamaguchi

Sarco-endoplasmic reticulum calcium release model based on changes in the luminal calcium content visualized from the luminal side

Agustín Guerrero-Hernández, Víctor Hugo Sánchez-Vázquez, Ericka Martínez-Martínez,

Lizeth Sandoval-Vázquez, Norma C. Perez-Rosas, Rodrigo Lopez-Farias, Adan Dagnino-Acosta


Pyridine Nucleotide Metabolites and Calcium Release from Intracellular Stores

Antony Galione and Kai-Ting Chuang


Calcium Signaling in the Heart

Derek A. Terrar


Molecular basis and regulation of store-operated calcium entry

Jose J Lopez, Isaac Jardin, Letizia Albarrán, Jose Sanchez-Collado, Carlos Cantonero, Gines M Salido, Tarik Smani and Juan A. Rosado

Structure and activation mechanisms of CRAC channels

Carmen Butorac, Adéla Krizova, Isabella Derler


Canonical Transient Potential Receptor-3 Channels in Normal and Diseased Airway Smooth Muscle Cells

Yong-Xiao Wang, Lan Wang, and Yun-Min Zheng


Pathophysiological significance of store-operated calcium entry in cardiovascular and skeletal muscle disorders and angiogenesis

Javier Avila-Medina, Isabel Mayoral-Sanchez, Isabel Galeano-Otero, Pedro C. Redondo, Juan A. Rosado, Tarik Smani


Calcium signalling and the regulation of chemosensitivity in cancer cells: role of the Transient Receptor Potential channels.

 Giorgio Santoni, Maria Beatrice Morelli, Oliviero Marinelli, Massimo Nabissi, Matteo Santoni, Consuelo Amantini.


Targeting Transient Receptor Potential Channels by microRNAs drives tumor development and progression.

Giorgio Santoni, Maria Beatrice Morelli, Matteo Santoni, Massimo Nabissi, Oliviero Marinelli and Consuelo Amantini


Calcium channels and Calcium-regulated channels in human red blood cells

Lars Kaestner, Anna Bogdanova, Stephane Egee


Regulation of multifunctional calcium/calmodulin stimulated protein kinases by molecular targeting

Kathryn Anne Skelding and John A. P. Rostas


Widespread roles of CaMK-II in Developmental Pathways


Sarah C. Rothschild and Robert M. Tombes


Readily releasable stores of calcium in neuronal endolysosomes: Physiological and pathophysiological relevance

Koffi L. Lakpa, Peter Halcrow, Xuesong Chen and Jonathan D. Geiger


At the crossing of ER stress and MAMs: A key role of Sigma-1 receptor?

Benjamin Delprat, Lucie Crouzier, Tsung-Ping Su, and Tangui Maurice


ER-mitochondria calcium transfer, organelle contacts and neurodegenerative diseases.

Francesca Vallese, Lucia Barazzuol, Lorenzo Maso, Marisa Brini and Tito Calì


 The Role of Mitochondrial Calcium Signaling in the Pathophysiology of Cancer Cells

Andra M Sterea and Yassine El Hiani


Calcium Signaling and Gene Expression

Basant K. Puri


Simulation Strategies for Calcium Microdomains and Calcium Noise

Nicolas Wieder, Rainer H. A. Fink, Frederic von Wegner


A statistical view on calcium oscillations

Jake Powell, Martin Falcke, Alexander Skupin, Tomas C Bellamy, Theodore Kypraios and Rüdiger Thul

Calcium Regulation of Bacterial Virulence

M. King, B. Kayastha, M. J. Franklin, M.A. Patrauchan

Ca2+ Signaling in Drosophila Photoreceptor Cells

Olaf Voolstra and Armin Huber


Calcium imaging in Drosophila melanogaster.

Nicola Vajente, Rosa Norante, Paola Pizzo and Diana Pendin.


Calcium imaging in the zebrafish

Petronella Kettunen


Stimulation-secretion coupling in the beta cells: from basic to bedside

Md. Shahidul Islam


Calcium dynamics and synaptic plasticity

Pedro Mateos-Aparicio and Antonio Rodríguez-Moreno


Calcium signaling during brain aging and its influence on the hippocampal synaptic plasticity

Ashok Kumar


Calcium Signaling in Endothelial Colony Forming Cells in Health and Disease

Francesco Moccia


Sensing Extracellular Calcium - An Insight into the Structure and Function of the Calcium-Sensing Receptor (CaSR)

Sergei Chavez-Abiega, Iris Mos, Patricia P. Centeno, Taha Elajnaf, Wolfgang Schlattl, Donald T. Ward, Joachim Goedhart, Enikö Kallay


Extracellular Ca2+ in bone marrow

Ryota Hashimoto


Calcium in Cell-Extracellular Matrix Interactions

Sandeep Gopal, Hinke A. B. Multhaupt, John R. Couchman



Titel: Calcium Signaling, 2 Teile
EAN: 9783030124564
ISBN: 978-3-030-12456-4
Format: Fester Einband
Herausgeber: Springer, Berlin
Genre: Medizin
Anzahl Seiten: 1110
Gewicht: g
Größe: H58mm x B236mm x T162mm
Jahr: 2019
Auflage: 2. Aufl.

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