Calcium Homeostasis

Volume III of this series deals with cellular calcium homeostasis aspects and structural properties of extra- and intracellular calcium-binding proteins are described. The structure/function relationship of calcium-transport proteins, and the role of calcium as a regulator of the activity specific protein kinases and phosphatase(s) are also described. The volume is a valuable source of information for graduate students and researchers who want to acquaint themselves with various aspects extracellular calcium. .

The companion book series to the "Journal of Biological Inorganic Chemistry" Includes supplementary material: sn.pub/extras

Klappentext

t organisms. A general outline of homeostasis, a dynamic balanced flow, is therefore described before a description of the systems in particular classes of organism. The organisms are treated in the sequence: prokaryotes, single-cell eukaryotes and, lastly, multicellular organisms reaching up to man.

Inhalt
Calcium Homeostasis and Its Evolution.- Evolution of EF-Hand Proteins.- Calmodulin Target Recognition: Common Mechanism and Structural Diversity.- Calcium-Binding EGF-like Domains.- Calmodulin-Dependent Protein Kinases.- Structure of Calcineurin and Its Complex with Immunophilins.- The Ca2+ Pump of Sarcoplasmic and Endoplasmic Reticulum Membranes.- The Plasma Membrane Ca2+ ATPase.- The Na+/Ca2+ Exchanger: Structural Aspects, Function and Regulation.