Muscle Contraction

L-------------------------------------------~ Kathy Ruppel, Ken Niebling and JeffFiner for their help and comments on the first draft. I am also grateful for discussions with and comments from Dr Neil Miliar, Professor Bob Simmons, Dr Roger Cooke, Dr Tosbio Yanagida, Dr John Kendrick-Jones, Dr Rob Cross, Dr Ian Trayer, Dr John Sparrow, Dr Michael Geeves, Dr Bernhard Brennerand Dr Peter K. night. The task of illustrating the book was made much easier by the photographs and diagrams kindly provided by Professor Ken Holmes, Dr Ron Milligan, Professor Basil Northover, Dr Hans Warrick, Dr John Squire, Dr JetT Harford, Dr Mary Reedy, Dr A vril Somlyo, Dr Darl Swartz, Dr Marion Greaser, Dr Peter Knight, Dr Gerald OtTer, Dr Roger Craig, Dr Peter Vibert, Dr John Kendrick-Jones, Dr Andrew Jackson, Dr Don Winkelmann, Dr Andrew Sowerby and Dr Richard Ankrett. I am grateful to the Science and Engineering Research Council for funding my travel to Stanford University. Permission to reproduce copyrighted material from the following publishers is gratefully acknowledged. The Physiological Society (Figs 2. 6, 6. 1, 6. 11, 6. 12, 7. 6), The RockefeBer University Press (Figs 3. 5, 4. 8, 8. 3), Academic Press(Figs3. 4,4. 4,4. 15, 9. 1, 9. 2), MacmillanPress(Figs 4. 2, 4. 3, 4. 12, 4. 13, 6. 6, 6. 9, 7. 8, 9. 3), Longman Group (Fig. 6. 7), The Royal Society (Fig. 3. 7) and D. W. Fawcett (Fig. 3. 1).

Klappentext

Movement in living organisms is achieved by many different mechanisms of which muscle contraction is one of the most studied and best understood. Nevertheless, the precise details of muscle action at the molecular level are still being evaluated. This book provides a concise account of our understanding to date.

Zusammenfassung
This volume, which explores the topic of muscle contraction across the diverse fields of physiology, biochemistry and biophysics, has been revised and updated in order to include material on recent advances in such areas as in vitro motility assays and molecular genetic approaches.

Inhalt
1 Introduction.- 2 Gross anatomy and physiology.- 3 Muscle cells.- 4 Contractile proteins.- 5 Mechanism of ATP hydrolysis.- 6 Crossbridge structure and function.- 7 Mechanochemical coupling.- 8 Molecular basis of regulation.- 9 In vitro motility assays.- 10 Problems and prospects.- References.