Blood cells in nuclear medicine, part I

xi List of first authors xiii Acknowledgements xv INTRODUCTICN Approaches to radiolabelling blood d-c cells: past, present and future M. L. Thakur 3 CELL LABELLllJG TEDlNIQUES 2 Labelling techniques of granulocytes and platelets 17 with 111 In-oxinate M. R. Hardeman, E. G. J. Eitjes-van Overbeek, A. J. M. van Velzen, M. H. Rovekarnp 111rndium-labelling of human washed platelets; kinetics 3 29 and in vivo sequestration sites M. Eber, J. P. Cazenave, J. C. Grob, J. Abecassis, G. !o1ethlin 111Indium loss from platelets by in vitro and ex 4 44 vivo manipulation R. J. Hawker, C. E. Hall, H. C-oldman, C. N. McCollum PIATELEl'S: KrnETIC STUDIES 5 The maturation of megakaryocytes and their precursors 65 J. H. Paulus 6 !o1egakaryocytic precursors 74 J. Breton-Gorius, W. Vainchenker 7 !-1ethods of quantification of platelet production 86 in man. A critical analysis Y. Najean vi 8 Platelet production rate deteDmination with (75se)_ seleno-m:thionine R. Cardinaud, E. Dassin 96 9 Platelet kinetics: the state of the art A. duP Heyns 110 10 Platelet kinetics A. M. Peters 130 Evaluation of models to deteDmine platelet life 11 span and survival curve shape M. G. LOtter, C. P. Herbst, P. N. Badenhorst, A. duP Heyns, P. Wessels, P. C. Minnaar 139 12 Canparison of three m:thods evaluating platelet survival tim: in patients with prosthetic heart valve J. Schbath, D. Ville, B. Hathy, B. Sanchini, E. Benveniste, J. Belleville, M. Dechavanne, J. P. Boissel, J.

Inhalt
1 Approaches to radiolabelling blood d-c cells: past, present and future.- Cell, Labelling Techniques.- 2 Labelling techniques of granulocytes and platelets with 111In-oxinate.- 3 111Indium-labelling of human washed platelets; kinetics and in vivo sequestration sites.- 4 111Indium loss from platelets by in vitro and ex vivo manipulation.- Platelets: Kinetic Studies.- 5 The maturation of megakaryocytes and their precursors.- 6 Megakaryocytic precursors.- 7 Methods of quantification of platelet production in man. A critical analysis.- 8 Platelet production rate determination with (75Se)-seleno-methionine.- 9 Platelet kinetics: the state of the art.- 10 Platelet kinetics.- 11 Evaluation of models to determine platelet life span and survival curve shape.- 12 Comparison of three methods evaluating platelet survival time in patients with prosthetic heart valve.- 13 In vivo kinetics of simultaneously injected 111In- and 51Cr-labelled human platelets: on the significance of the platelet isolation yield from blood prior to labelling.- 14 Simultaneous kinetics and external countings of autologous 111In-oxine labelled platelets and homologous 51Cr labelled platelets.- 15 Platelet survival time (51Cr) and platelet production time (Aspirin-MDA method): a simultaneous evaluation in patients affected with cancers.- Labelled Platelets: Scintigraphic Studies.- 16 Survival time and organ distribution of 111In-oxine-labelled human platelets in normal subjects.- 17 111In-labelled platelets in the diagnosis of kidney transplant rejection.- 18 Continuous monitoring of human kidney transplants by autologous labelled platelets.- 19 Use of 111In-labelled platelets in cardiovascular disease.- 20 Homocystinuria: kinetics and distribution of 111In-labelled platelets.- 21 Noninvasive radioisotopic techniques for detection of platelet deposition in mechanical and bovine pericardial mitral valve prostheses and in vitro quantitation of visceral microembolism.- Platelets, Beta-Thromboglobulin, Platelet Factor 4.- 22 Beta-thromboglobulin, present state of the art.- 23 Beta-thromboglobulin and platelet factor 4 in polycythemia and thranbocythemia.- 24 Beta-thromboglobulin, platelet factor 4 and coronary heart disease.- 25 Beta-thromboglobulin release and thranboxane synthesis in diabetic platelets: effect of glycemic control and retinopathy.- 26 Hemorheology and platelet activation: theoretical and experimental aspects.- Granulocytes.- 27 111In-leukocyte scintigraphy in the diagnosis of vascular graft infection.- 28 Diagnosis of intra abdominal inflammatory processes with 111In-labelled leucocytes.- 29 111In-autologous leucocytes in the diagnosis and management of inflammatory bowel disease.- 30 Diagnosis of orthopedic prostheses infection with 111In-labelled leucocytes.- 31 Radiation dosimetry of 111In-oxinate labeled leucocytes.- Lymphocytes.- 32 The lymphocyte in Hodgkin's disease: has it lost its way?.- 33 Labelling of human lymphocytes with 111In-oxinate.- Erythrocytes.- 34 Tc99m labelling of red blood-cells and their clinical application.