Klappentext

Biomaterials and Regenerative Medicine in Ophthalmology, 3rd Edition is thoroughly revised and expanded, including 8 new chapters which offer greater focus on corneal and retinal reconstruction, using specialised ophthalmic biomaterials. The book is divided into five essential parts, beginning with an introduction and outlining the biomaterial-ocular surface interface, laying the foundation with materials, properties, tissue interaction, and design coverage. The subsequent sections systematically cover strategies for reconstruction, before exploring other applications, as well as industry and clinical perspectives. Detailed methods for the design and development of ophthalmic biomaterials are outlined, along with supporting industry and clinical case studies, to offer practical insights and allow for improved translation into research and therapeutics. Biomaterials and Regenerative Medicine in Ophthalmology, 3rd Edition is suitable for researchers, academics, and postgraduate students wanting to gain a deeper understanding of ophthalmic biomaterials and regenerative medicine in ophthalmology. This book may also be of interest to R&D groups developing novel ophthalmic biomaterials, as well as clinicians and ophthalmologists with an interest in biomaterials and regenerative strategies.

Inhalt

Part One: Biomaterial-Ocular Surface Interface

1. Ocular biotribology and the ocular/contact lens interface
2. The ageing tear film and ocular surface: biomaterials challenges
3. The design and development of hydrogels and silicone hydrogels for contact lens applications

4. Advances in contact lens design

   Part Two: Strategies for Corneal Reconstruction

5. The strengths and limitations of primary corneal cells
6. Potential for corneal cells from iPS cells
7. Biomaterials for repairing the corneal epithelium
8. Biomaterials for stromal reconstruction
9. Kuragel - Liquid cornea

10. Biomaterials for corneal endothelial cell transplantation

    Part Three: Strategies for Retinal Reconstruction

11. Biomaterials for retinal tissue engineering
12. Neural retina
13. RPE and choroid

14. Optic nerve

    Part Four: Biomaterials for Ocular Drug Delivery

15. Topical delivery of ophthalmic drugs
16. Slow-release drug platforms for ophthalmology
17. Slow-release glaucoma drug delivery systems

18. Intra-vitreal drug delivery

    Part Five: Other Applications

19. Hydrogels for ophthalmological use: physiochemical and structural considerations
20. Polymer science in glaucoma implants
21. Advances in intraocular lenses
22. Vitreal substitutes
23. Keratoprotheses
24. Orbital implants
25. Retinal prostheses - lessons learned
26. IOP monitoring systems