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Bioinformatics for Comparative Proteomics

  • Kartonierter Einband
  • 404 Seiten
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This book covers bioinformatics frameworks relating to comparative proteomics, bioinformatics databases and tools for proteomics d... Weiterlesen
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Beschreibung

This book covers bioinformatics frameworks relating to comparative proteomics, bioinformatics databases and tools for proteomics data analysis, and integrated systems and approaches to studying comparative proteomics in the systems biology context.


With the rapid development of proteomic technologies in the life sciences and in clinical applications, many bioinformatics methodologies, databases, and software tools have been developed to support comparative proteomics study. In Bioinformatics for Comparative Proteomics, experts in the field highlight the current status, challenges, open problems, and future trends for developing bioinformatics tools and resources for comparative proteomics research in order to deliver a definitive reference providing both the breadth and depth needed on the subject. Structured in three major sections, this detailed volume covers basic bioinformatics frameworks relating to comparative proteomics, bioinformatics databases and tools for proteomics data analysis, and integrated bioinformatics systems and approaches for studying comparative proteomics in the systems biology context. Written for the highly successful Methods in Molecular Biology(TM) series, the contributions in this book provide the meticulous, step-by-step description and implementation advice that is crucial for getting optimal results in the lab.

Comprehensive and easy-to-use, Bioinformatics for Comparative Proteomics serves all readers who wish to learn about state-of-the-art bioinformatics databases and tools, novel computational methods and future trends in proteomics data analysis, and comparative proteomics in systems biology.

From the reviews:

This book provides comprehensive coverage of the current status, challenges, open problems, and future trends in developing bioinformatics tools and resources for comparative proteomics research. The audience ranges from graduate students embarking upon a research project to practicing biologists and bioinformaticians. This broad audience working in biotechnology and pharmaceutical companies and in various academic departments will find this book quite useful. This well-illustrated book is a comprehensive resource on bioinformatics for comparative proteomics. (Omer Iqbal, Doody's Book Reviews, March, 2012)

Inhalt

Part I: Bioinformatics Framework for Comparative Proteomics

1. Protein Bioinformatics Databases and Resources
Chuming Chen, Hongzhan Huang, and Cathy H. Wu

2. A Guide to UniProt for Protein Scientists
Claire O'Donovan and Rolf Apweiler

3. InterPro Protein Classification
Jennifer McDowall and Sarah Hunter

4. Reactome Knowledgebase of Human Biological Pathways and Processes
Peter D'Eustachio

5. eFIP: A Tool for Mining Functional Impact of Phosphorylation from Literature
Cecilia N. Arighi, Amy Y. Siu, Catalina O. Tudor, Jules A. Nchoutmboube, Cathy H. Wu, and Vijay K. Shanker

6. A Tutorial on Protein Ontology Resources for Proteomic Studies
Cecilia N. Arighi

7. Structure-Guided Rule-Based Annotation of Protein Functional Sites in UniProt Knowledgebase
Sona Vasudevan, C.R. Vinayaka, Darren A. Natale, Hongzhan Huang, Robel Y. Kahsay, and Cathy H. Wu

Part II: Proteomic Bioinformatics

8. Modeling Mass Spectrometry-Based Protein Analysis
Jan Eriksson and David Fenyö

9. Protein Identification from Tandem Mass Spectra by Database Searching
Nathan J. Edwards

10. LC-MS Data Analysis for Differential Protein Expression Detection
Rency S. Varghese and Habtom W. Ressom

11. Protein Identification by Spectral Networks Analysis
Nuno Bandeira

12. Software Pipeline and Data Analysis for MS/MS Proteomics: The Trans-Proteomic Pipeline
Andrew Keller and David Shteynberg

13. Analysis of High-Throughput ELISA Microarray Data
Amanda M. White, Don S. Daly, and Richard C. Zangar

14. Proteomics Databases and Repositories
Lennart Martens

15. Preparing Molecular Interaction Data for Publication
Sandra Orchard and Henning Hermjakob

16. Submitting Proteomics Data to PRIDE Using PRIDE Converter
Harald Barsnes, Juan Antonio Vizcaíno, Florian Reisinger, Ingvar Eidhammer, and Lennart Martens

17. Automated Data Integration and Determination of Posttranslational Modi cations with the Protein Inference Engine
Stuart R. Jefferys and Morgan C. Giddings

18. An Integrated Top-Down and Bottom-Up Strategy for Broadly Characterizing Protein Isoforms and Modifications
Si Wu, Nikola Tolic, Zhixin Tian, Errol W. Robinson, and Ljiljana PaSa-Tolic

Part III: Comparative Proteomics in Systems Biology

19. Phosphoproteome Resource for Systems Biology Research
Bernd Bodenmiller and Ruedi Aebersold

20. Protein-Centric Data Integration for Functional Analysis of Comparative Proteomics Data
Peter B. McGarvey, Jian Zhang, Darren A. Natale, Cathy H. Wu, and Hongzhan Huang

21. Integration of Proteomic and Metabolomic Profiling as well as Metabolic Modeling for the Functional Analysis of Metabolic Networks
Patrick May, Nils Christian, Oliver Ebenhöh, Wolfram Weckwerth, and Dirk Walther

22. Time Series Proteome Profiling
Catherine A. Formolo, Michelle Mintz, Asako Takanohashi, Kristy J. Brown, Adeline Vanderver, Brian Halligan, and Yetrib Hathout

Produktinformationen

Titel: Bioinformatics for Comparative Proteomics
Editor:
EAN: 9781493957903
ISBN: 1493957902
Format: Kartonierter Einband
Herausgeber: Humana Press
Anzahl Seiten: 404
Gewicht: 757g
Größe: H254mm x B178mm x T21mm
Jahr: 2016
Auflage: Softcover reprint of the original 1st ed. 2011

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