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Bacterial Therapy of Cancer

  • Fester Einband
  • 186 Seiten
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This volume explores the evolution of bacterial cancer therapy and describes the modern techniques used in therapy today. The chap... Weiterlesen
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This volume explores the evolution of bacterial cancer therapy and describes the modern techniques used in therapy today. The chapters in this book cover a broad range of topics such as the development of tumor-targeting Salmonella typhimurium A1-R, a microfluidic device for precise quantification of the interactions between tumor-targeting bacteria and tumor tissue, non-invasive in vivo imaging of bacteria-mediated cancer therapy using bio-luminescent bacteria, methods to achieve remote-control of therapeutic gene expression in tumor-targeting bacteria, and cell-cycle decoy of cancer cells resistant to cytotoxic drugs to drug sensitivity by S. typhimurium A1-R. This book concludes with a chapter on the future potential of bacterial therapy of cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Thorough and informative, Bacterial Therapy of Cancer: Methods and Protocols is a valuable resource for anyone who is interested in cancer and bacterial therapy.

Includes cutting-edge methods and protocols

Provides step-by-step detail essential for reproducible results

Contains key notes and implementation advice from the experts

Robert M. Hoffman, Ph.D. Professor of Surgery, University of California, San Diego President, AntiCancer, Inc. 7917 Ostrow Street San Diego, CA 92111 USA TEL: 1-858-654-2555 FAX: 1-858-268-4175 Email: all@anticancer.com

1. Tumor Targeting Salmonella Typhimurium A1-R: An OverviewRobert M. Hoffman2. Enhancement of Tumor-Targeted Delivery of Bacteria with Nitroglycerin Involving Augmentation of the ERP EffectJun Fang, Lio Long, and Hiroshi Maeda3. Oral Delivery of Tumor-Targeting Salmonella to Treat Cancer in MiceDongping Wei and Lijun Jia4. Microfluidic Device to Quantify the Behavior of Therapeutic Bacteria in Three-Dimensional Tumor TissueEmily L. Brackett, Charles A. Swofford, and Neil S. Forbes5. Tumor-Targeting Therapy Using Gene-Engineered Anaerobic-Nonpathogenic Bifidobacterium LongumShun'ichiro Taniguchi, Yuko Shimatani, and Minoru Fujimori6. Noninvasive In Vivo Imaging to Follow Bacteria Engaged in Cancer TherapySara Lerchner and Siegfried Wiess7. In Vivo Bioluminescence Imaging of Intra-Tumoral BacteriaMichelle Cronin, Ali R. Akin, Kevin P. Francis, and Mark Tangney8. Employment of Salmonella in Cancer Gene TherapyChe-Hsin Lee9. Development of a Targeted Gene Delivery System Using Escherichia ColiChung-Jen Chiang, Chih-Hsiang Chang, Yun-Peng Chao, and Ming-Ching Kao10. Isolation and Analysis of Suppressor Mutations in Tumor-Targeted msbB SalmonellaK. Brooks Low, Sean R. Murray, John Pawelek, and David Bermudes11. Determination of Plasmid Segregational Stability in a Growing Bacterial PopulationM. Gabriela Kramer12. Visualization of Anti-Cancer Salmonella Typhimurium Engineered for Remote-Control of Therapeutic ProteinsVu H. Hguyen and Jung-Joon Min13. Methods for Tumor Targeting with Salmonella Typhimurium A1-RRobert M. Hoffman14. Salmonella Typhimurium A1-R and Cell-Cycle Decoy Therapy of CancerRobert M. Hoffman15. Future of Bacterial Therapy of CancerRobert M. Hoffman


Titel: Bacterial Therapy of Cancer
Untertitel: Methods and Protocols
EAN: 9781493935130
ISBN: 978-1-4939-3513-0
Format: Fester Einband
Herausgeber: Springer, Berlin
Genre: Medizin
Anzahl Seiten: 186
Gewicht: g
Größe: H16mm x B264mm x T184mm
Jahr: 2016
Auflage: 1st ed. 2016

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