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Angiogenesis in Health and Disease

  • Kartonierter Einband
  • 416 Seiten
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Proceedings of a NATO ASI held in Porto Hydra, Greece, June 16-27, 1991Angiogenesis describes the formation of new blood vessels, ... Weiterlesen
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Beschreibung

Proceedings of a NATO ASI held in Porto Hydra, Greece, June 16-27, 1991

Angiogenesis describes the formation of new blood vessels, which arise as outgrowths from existing vessels. In many physiological processes such as ovulation and wound healing angiogenesis is involved for a relatively short time. Otherwise under normal physiological conditions in the adult organism angiogenesis is an extremely slow process. By contrast in certain disease states such as diabetic retinopathy, arthritis, chronic inflammation, hemangiomas, etc., angiogenesis persists and contributes to the pathology of these disease states. Some 50 such "angiogenic diseases" have been described where angiogeneSiS is involved. Also in tumor growth and metastasis angiogenesis is an essential process and precedes neoplastic transformation. Hence, angiogenesis could become an important diagnostic tool and a target for developing therapeutic agents. This book contains the proceedings of the NATO Advanced Study Institute on "Angiogenesis in Health and Disease" held in Porto Hydra, Greece, from June 16-27, 1991. This meeting was a comprehensive review of endothelial cell biology and endothelial cell phenotypic and functional heterogeneity in relation to angiogenesis under physiological and pathological conditions. Numerous in vitro and in vivo models were presented, which are used to study angiogenesis at the molecular and cellular levels and to evaluate chemical compounds or naturally occuring substances for their effect on angiogenesis. The presentations and discussions at this meeting provided an opportunity for the basic science and the clinical disciplines to meet, exchange information and provide future research directions for many investigators engaged in the study of angiogenesis.

Klappentext

Proceedings of a NATO ASI held in Porto Hydra, Greece, June 16-27, 1991



Zusammenfassung
Proceedings of a NATO ASI held in Porto Hydra, Greece, June 16-27, 1991

Inhalt
The Development of the Vascular System: Embryonic Development of Blood Vessels; F. Dieterlen-Liévre, L. Pardanaud. Regulation of Embryonic Blood Vessel; H. Drexler et al.. Biology of Endothelial Cells and Angiogenesis: Basic Fibroblast Growth Factor and Endothelial Cells; M. Presta, et al. Role of Integrinss in Endothelial Cell Function; E. Dejana, et al. Angiogenesis in Disease States: Angiogenesis and Neoplastic Transformation; P.M. Gullino. Tumor Induced Angiogenesis; J.L. Ambrus, et al. Promoters and Inhibitors of Angiogenesis: Brain Tumor Angiogenesis; C. Guerin, et al. Therapeutic Potential of Promoters and Inhibitors of Angiogenesis: On Promoter of Angiogenesis and Therapeutic Potential; P.M. Gullino. Methodology: Assays for Angiogenic Factors; J.B. Weiss. 23 additional articles. Index.

Produktinformationen

Titel: Angiogenesis in Health and Disease
Editor:
EAN: 9781461364818
ISBN: 1461364817
Format: Kartonierter Einband
Herausgeber: Springer US
Genre: Medizin
Anzahl Seiten: 416
Gewicht: 656g
Größe: H244mm x B156mm x T22mm
Jahr: 2012
Untertitel: Englisch
Auflage: Softcover reprint of the original 1st ed. 1992

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