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Novel use of Thymol and Carvacrol

  • Kartonierter Einband
  • 140 Seiten
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The main dose-limiting side effect of cisplatin (CP) is nephrotoxicity. Yet, in spite of intense efforts over the ensuing decades ... Weiterlesen
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Beschreibung

The main dose-limiting side effect of cisplatin (CP) is nephrotoxicity. Yet, in spite of intense efforts over the ensuing decades to find less toxic but equally effective alternatives, CP continues to be widely prescribed. It remains as a standard component of treatment regimens for head and neck cancers, testicular cancer, small-cell and non-small cell lung cancer, ovarian, cervical cancer, bladder cancer and others. Monoterpenes are highly hydrophobic substances present in plant essential oils. They exert a wide spectrum of biological actions of great importance in many different areas. Two monoterpenes of the Lamiaceae that have attracted much attention, thymol and carvacrol. Hence, this study was aimed to investigate the efficacy of thymol and CAR or their combination in ameliorating the toxic effects via inhibition of oxidative damage, inflammation and apoptosis induced by CP in rats.

Autorentext

I received my B.Sc. from Pharmacy College AL-Azhar University in 2007 (with general Degree: Excellent with Honor Degree),my M.D.from Pharmacy College AL-Azhar University in Pharmaceutical Sciences (Pharmacology & Toxicology)-2015; under supervision: Prof.Dr.El-Sayed Mohamed El-Sayed,Prof.Dr.Adel Rashad Ahmed Abd-Allah and Dr.Ahmed Mohamed Ibrahim.

Produktinformationen

Titel: Novel use of Thymol and Carvacrol
Untertitel: Evaluation of possible protective effects of thymol and carvacrol against cisplatin-induced nephrotoxicity in rats
Autor:
EAN: 9783659712470
ISBN: 978-3-659-71247-0
Format: Kartonierter Einband
Herausgeber: LAP Lambert Academic Publishing
Genre: Biologie
Anzahl Seiten: 140
Gewicht: g
Größe: H220mm x B220mm x T150mm
Jahr: 2015