Actin-Monomer-Binding Proteins

The actin cytoskeleton plays a central role in many cellular processes including cell motility, cytokinesis, endocytosis and phagocytosis. The structure and dynamics of the actin cytoskeleton is regulated by a large number of proteins that interact with monomeric and/or filamentous actin. Actin monomer binding proteins provides a comprehensive view on actin monomer-binding proteins and the mechanisms by which they contribute to actin dynamics and various actin-dependent cellular processes. This new title contains chapters that describe the basic mechanisms of actin dynamics as well as the structural principles by which various actin-binding proteins interact with actin.

The most fundamental actin monomer-binding proteins are described in independent chapters written by world's foremost experts on these proteins Suitable further reading for students in advanced cell biology classes

Inhalt
How Actin Assembly Is Modulated at Filament Barbed Ends in Motile Processes.- Proteins of the Actin Depolymerizing Factor/Cofilin Family.- Profilin, an Essential Control Element for Actin Polymerization.- Srv2/Cyclase-Associated Protein (CAP).- Twinfilin Family of Actin Monomer-Binding Proteins.- Intracellular ?-Thymosins.- Multirepeat ?-Thymosins.- Wasp and WAVE Family Proteins.- The Verprolins as Regulators of Actin Dynamics.- A Common Binding Site for Actin-Binding Proteins on the Actin Surface.