Comparative Genomics

Fungal comparative genomics started in 2000 by the genome sequencing of several yeast species. Since then, over 30 fungal genome sequences have become available. This set represents a huge evolutionary divergence, but also contains closely related genomes. This volume describes how to use this set of genomes to trace events in genome evolution, to extract information about highly conserved and less conserved sequence elements, and to develop novel methods in genomics.

Inhalt

Comparative Genomics and Gene Finding in Fungi.- Taxonomy and Phylogenetic Diversity Among the Yeasts.- Structural Features of Fungal Genomes.- Duplication of Genes and Genomes in Yeasts.- Telomeres in Fungi.- Employing Protein Size in the Functional Analysis of Orthologous Proteins, as Illustrated With the Yeast HOG Pathway.- Lager Brewing Yeast.- Genome Evolution: Lessons from Genolevures.- The Genome of the Filamentous Fungus Ashbya gossypii: Annotation and Evolutionary Implications.- Schizosaccharomyces pombe Comparative genomics; from Sequence to Systems.