Handbook of Parkinson's Disease

Now in its fifth edition, this volume is a comprehensive review of all aspects of Parkinson's disease. The contributors discuss early manifestations leading to diagnosis, genetics epidemiology, and the use of animal models for diagnosis and treatment. Additional focused areas include sleep dysfunction, neuropsychological aspects, neuroimaging, and the management of anxiety, depression, psychosis, and dementia, as well as motor and non-motor management and surgical treatments. Also discussed are various non-pharmacologic approaches, including physical and occupational therapy. In addition, they review potential treatments currently being investigated.

Autorentext

**Rajesh Pahwa MD is a clinician and Laverne and Joyce Rider Professor of Neurology and Director of the Parkinson's Disease and Movement Disorder Center, University of Kansas Medical Center. Kelly E Lyons PhD **is Director of Research and Education at the Parkinson's Disease and Movement Disorder Center, University of Kansas Medical Center.

Zusammenfassung
Highly Commended, BMA Medical Book Awards 2014This volume has long prevailed as one of the leading resources on Parkinson's disease (PD). Fully updated with practical and engaging chapters on pathology, neurochemistry, etiology, and breakthrough research, this source spans every essential topic related to the identification, assessment, and treatment of PD.Reflecting the many advances that have taken place in the management of PD, this volume promotes a multidisciplinary approach to care and supplies new sections on the latest pharmacologic, surgical, and rehabilitative therapies, as well as essential diagnostic, imaging, and nonmotor management strategies.New to this edition: Early identification of premotor symptoms Potential disease modification agents Physical and occupational therapy

Inhalt

Early Iconography of Parkinson's Disease. Epidemiology. Differential Diagnosis. Pathophysiology and Clinical Assessment. Premotor Symptoms. Autonomic Dysfunction and Management. Sleep Dysfunction. Neuropsychological Aspects. Management of Anxiety and Depression. Management of Psychosis and Dementia. Neuroimaging. Neuropathology. Neurophysiology and Neurocircuitry. Animal Models. Genetics. Environmental Risk Factors. Disease Modification. Amantadine and Anticholinergics. Levodopa. Dopamine Agonists. MAO inhibitors. COMT Inhibitors. Investigational Pharmacological Treatments. Deep Brain Stimulation. Investigational Surgical Therapies. Physical and Occupational Therapy. Voice, Speech and Swallowing Disorders. Alternative Therapies.