Design and Development of Medical Electronic Instrumentation

Design and Development of Medical Electronic Instrumentation fills a gap in the existing medical electronic devices literature by providing background and examples of how medical instrumentation is actually designed and tested. The book includes practical examples and projects, including working schematics, ranging in difficulty from simple biopotential amplifiers to computer-controlled defibrillators. Covering every stage of the development process, the book provides complete coverage of the practical aspects of amplifying, processing, simulating and evoking biopotentials. In addition, two chapters address the issue of safety in the development of electronic medical devices, and providing valuable insider advice.

Autorentext

DAVID PRUTCHI, PhD, received his doctorate in biomedical
engineering from Tel-Aviv University, Israel. Currently, he is Vice
President of Product Development for Impulse Dynamics. He has over
fifteen years of experience in biomedical and medical electronic
instrumentation research, design, and management. He has published
over thirty papers and holds over sixty patents in the field of
active implantable medical devices.

MICHAEL NORRIS is a senior electronics engineer for Impulse
Dynamics. He has over twenty-five years of experience as a medical
device designer, including research, design and development of
analog and digital circuits, microprocessors, and embedded
software.

Klappentext
Master the building blocks of medical devices with this hands-on guide This book provides a uniquely practical approach that enables readers to learn the design of medical electronic devices through the analysis of specific projects. Walking you through the building blocks of implementing medical devices, Design and Development of Medical Electronic Instrumentation addresses the practical aspects of amplifying, processing, simulating, and evoking biopotentials. It provides real-world projects that range from simple biopotential amplifiers all the way to a computer-controlled defibrillator. Anyone with a basic understanding of circuit design and electrical engineering mathematics and experience in electronic prototype construction will find these projects accessible. Chapters discuss:

• Biopotential amplifiers, including a refresher on the origin and acquisition of physiological electrical signals
• Spectral content of biosignals, filter design, and the selection of frequency ranges for biopotential amplifiers
• Design of safe medical device prototypes
• International regulations and design practices for electromagnetic compatibility of medical devices
• Data acquisition, smart sensors, analog-to-digital conversion, and high-resolution spectral analysis of physiological signals
• Artificial signal sources for simulating physiological events
• Principles, clinical applications, and design of excitable tissue stimulators
• Design of cardiac pacemakers and defibrillators, including a refresher on the electrophysiology of the heart, its conduction deficiencies, and arrhythmias
  With access to an ftp site that contains the software and information needed to successfully complete the projects outlined, plus a special epilogue on how to bring a medical device to market, this book will help one quickly master the essentials of medical device design and build sophisticated instrumentation for a broad range of purposes.

Inhalt

PREFACE ix

DISCLAIMER xiii

ABOUT THE AUTHORS xv

1 BIOPOTENTIAL AMPLIFIERS 1

2 BANDPASS SELECTION FOR BIOPOTENTIAL AMPLIFIERS 41

3 DESIGN OF SAFE MEDICAL DEVICE PROTOTYPES 97

4 ELECTROMAGNETIC COMPATIBILITY AND MEDICAL DEVICES 147

5 SIGNAL CONDITIONING, DATA ACQUISITION, AND SPECTRAL ANALYSIS 205

6 SIGNAL SOURCES FOR SIMULATION, TESTING, AND CALIBRATION 249

7 STIMULATION OF EXCITABLE TISSUES 305

8 CARDIAC PACING AND DEFIBRILLATION 369

EPILOGUE 441

APPENDIX A: SOURCES FOR MATERIALS AND COMPONENTS 447

APPENDIX B: ACCOMPANYING CD-ROM CONTENT 451

INDEX 457