Cytokine Effector Functions in Tissues

Cytokine Effector Functions in Tissues discusses the cytokines networks in the context of the specific-tissue environment. It is an up-to-date collection of articles that addresses the specific issue of how the cytokines are able to condition tissue specific homeostasis. The book helps the reader understand how cytokines network inside the tissues and highlights whether tissue-protection or exacerbation will be finally controlled. It describes the cytokines detected and regulated in different tissues, such as the brain, lungs, spleen, liver, pancreas and intestine, also addressing the issue of timing in specific cell types.

• Categorizes the cytokines based primarily on tissue and target cells
• Emphasizes different roles and outcomes observed during innate and adaptive response
• Represents a rapid guide to cytokines in health and disease in tissue and organ context
• Presents a different view on how known mediators may work if analyzed in a different perspective, determining the final outcome on tissue-specific target cells

Inhalt

I. Cytokine Tissue Specific Regulation 1. Cytokine and the Adipose Tissue 2. Cytokine and Ovary 3. Cytokine and the Liver

II. Cytokine Regulation in Disease 4. Cytokines in Osteoarthritis 5. Cytokines in Atherosclerosis 6. Cytokines and Diabetes 7. Cytokines and Sarcoidosis 8. Cytokine and Nerve Degeneration 9. Cytokine and Skeletal Muscle Disease 10. Airway epithelial cytokines in asthma and chronic obstructive pulmonary disease 11. Eosinophils Cytokines and Allergies 12. Cytokine in Transplantation

III. Cytokines and Therapeutic Applications 13. Cytokine Therapies in CANCER 14. MSCs Cytokines as cellular Therapies