Cyclodextrins in Pharmaceutics, Cosmetics, and Biomedicine

Cyclodextrins in Pharmaceutics, Cosmetics, and Biomedicine covers a wide range of knowledge on cyclodextrins, from an overview of molecular and supramolecular aspects of cyclodextrin physicochemistry, to the latest outcomes in cyclodextrin use and future possibilities in the employment of these systems. This book focuses on the derivatives and physicochemical and biological properties of cyclodextrins, and considers drug delivery through topical, mucosal, and oral via cyclodextrin complexes.

Autorentext
Erem Bilensoy, PhD, is a Professor of Pharmaceutical Technology at Hacettepe University in Turkey. Dr. Bilensoy has published more than forty articles in international peer-reviewed journals as well as six book chapters on cyclodextrins.

Klappentext
An in-depth look at the state of the art of cyclodextrin applications Owing to their unique properties, cyclodextrin complexes are finding new applications in food, pharmaceuticals, and biomedical research, among others. This book covers the scientific essentials of cyclodextrins along with a thorough review of their applications, providing an authoritative, up-to-date reference to this evolving field.

Written by an international group of experts, the book explores a wide range of vital topics, from pharmaceutical usage to innovative drug delivery systems to drug-targeting strategies using cyclodextrin derivatives. The authors discuss physicochemical and biological properties, examine the latest outcomes in cyclodextrin use, and consider every step of the way for both present and future applications. Coverage includes:

• The molecular and supramolecular aspects of cyclodextrin physicochemistry

• Applications of cyclodextrins in different delivery routes, including topical, mucosal, and oral

• The advantages of using cyclodextrins as excipients in pharmaceutical formulations and effect on bioavailability of drugs as a result of cyclodextrin complexation

• Cyclodextrin-based nanoparticles, nanosponges, nanoassemblies, and hydrogels

• Gene delivery, biotechnology applications, and cellular interactions

• The regulatory status and safety profiles of cyclodextrins

Cyclodextrins in Pharmaceutics, Cosmetics, and Biomedicine is an essential resource for researchers in pharmaceuticals, biomedicine, food, and cosmetics, as well as professionals working with pharmaceutical formulations and novel drug-delivery systems.

Zusammenfassung
Cyclodextrins in Pharmaceutics, Cosmetics, and Biomedicine covers a wide range of knowledge on cyclodextrins, from an overview of molecular and supramolecular aspects of cyclodextrin physicochemistry, to the latest outcomes in cyclodextrin use and future possibilities in the employment of these systems. This book focuses on the derivatives and physicochemical and biological properties of cyclodextrins, and considers drug delivery through topical, mucosal, and oral via cyclodextrin complexes.

Inhalt

Contributors.

Preface.

Part I. Cyclodextrins: History, Properties, Applications, and
Current Status.

1. Cyclodextrins and Their Inclusion Complexes (Dominique
   Duchêne).

2. Cyclodextrins as Potential Excipients in Pharmaceutical
   Formulations: Solubilizing and Stabilizing Effetcts (Alka Ahuja,
   Sanjula Baboota, Javed Ali, and Gulam Mustafa).

3. Cyclodextrins as Bioavailability Enhancers (Füsun
   Acartürk and Nevin Çelebi).

4. Cyclodextrins as Smart Excipients in Polymeric Drug Delivery
   Systems (Agnese Miro, Francesca Ungaro, and Fabriana
   Quaglia).

5. Recent Findings on Safety Profiles of Cyclodextrins,
   Cyclodextrin Conjugates, and Polypseudorotaxanes (Hidetoshi
   Arima, Keiichi Motoyama, and Tetsumi Irie).

6. Regulatory Status of Cyclodextrins in Pharmaceutical Products
   (A. Atilla Hincal, Hakan Eroglu, and Erem Bilensoy).

7. Cyclodextrins in the Cosmetic Field (Nilüfer
   Tarimci).

8. Cyclodextrin-Enhanced Drug Delivery Through Mucous Membranes
   (Phatsawee Jansook, Marcus E. Brewster, and Thorsteinn
   Loftsson).

9. Applications of Cyclodextrins for Skin Formulation and
   Delivery (Amélie Bochot and Géraldine Piel).

10. Oral Drug Delivery with Cyclodextrins (Francisco Veiga,
    Ana Rita Figueiras, and Amelia Vieira).

Part II. Novel and Specialized Applications of
Cyclodextrins.

11. Amphiphilic Cyclodextrins: Synthesis and Characterization
    (Florent Perret and Hélène Parrot-Lopez).

12. Gene Delivery with Cyclodextrins (Véronique Wintgens
    and Catherine Amiel).

13. Targeted Cyclodextrins (Stefano Salmaso and Fabio
    Sonvico).

14. Cyclodextrins and Biotechnological Applications (Amit
    Singh, Abhishek Kaler, Vachan Singh, Rachit Patil, and Uttam C.
    Banerjee).

15. Cyclodextrins and Cellular Interactions (Justin M.
    Dreyfuss and Steven B. Oppenheimer).

16. Cyclodextrins-Based Hydrogels (Carmen Alvarez-Lorenzo,
    Maria D. Moya-Ortega, Thorsteinn Loftsson, Angel Concheiro, and
    Juan J. Torres-Labandeira).

17. Cyclodextrin Nanosponges and Their Applications
    (Francesco Trotta).

18. Photodynamic Tumor Therapy with Cyclodextrin Nanoassemblies
    (Antonino Mazzaglia).

19. Sugammadex: A Cyclodextrin-Based Novel Formulation and
    Marketing Story (François Donati).

20. Cyclodextrins and Polymer Nanoparticles (Dominique
    Duchêne and Ruxandra Gref).

Index.