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Acriflavin Inhibits the Proliferation of Trypanosomamusculi

  • Kartonierter Einband
  • 128 Seiten
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In Africa, it is estimated that trypanosomiasis occurs in more than 37 Sub-Saharan countries covering more than a third of Africa ... Weiterlesen
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Beschreibung

In Africa, it is estimated that trypanosomiasis occurs in more than 37 Sub-Saharan countries covering more than a third of Africa s total area. The infection threatens an estimated 60 million people and about 50 million cattle. According to the World Health Organization (WHO, 2002), estimation about 500,000 new cases of human infection and 3 million deaths in cattle occur every year. The economic losses in cattle production alone are estimated to be about 1.2 billion U.S dollars a year. If this figure were extrapolated to the whole tsetse infested land, the total losses in terms of agricultural Gross Domestic Product, would amount to $ 4.75 billion dollars per year (WHO, 2002). As of now, there is no efficient and safe enough drug to be used as the first-line drug to fight trypanosomiasis (Jarvinen and Dalmasso, 1977; Fong et al., 1984; Odeika et al., 1994; Obexer et al., 1995; Gubler, 1998; Klingbeil and Englund, 2004). The urgent need for more selective and less toxic antitrypanosomiasis drug has stimulated this study of acriflavine as a possible antitrypanosomial drug.

Autorentext

Ph.D in Biology, Howard University Washington DC, 2007 Bachelor of Science in Chemistry, UDC, Washington DC, 2001 Bachelor of Science in Statistics, Addis Ababa University Addis Ababa, Ethiopia, 1988 2001 College Chemistry Achievement Award; The Chemical Society of Washington. 2001 Students Award; The American Institutes of Chemists.

Produktinformationen

Titel: Acriflavin Inhibits the Proliferation of Trypanosomamusculi
Untertitel: by Inducing Apoptosis with Specific BindingAffinity to KDNA of the Parasite
Autor:
EAN: 9783639094671
ISBN: 978-3-639-09467-1
Format: Kartonierter Einband
Herausgeber: VDM Verlag
Genre: Allgemeines & Lexika
Anzahl Seiten: 128
Gewicht: 207g
Größe: H220mm x B150mm x T8mm
Veröffentlichung: 01.01.2009
Jahr: 2009
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