Inspiring and motivating students from the moment it published, Organic Chemistry has established itself in just one edition as the students' choice of organic chemistry text. Its explanatory, mechanistic, evidence-based approach makes it perfect for fostering a true understanding of the subject.

Autorentext

Jonathan Clayden is a Professor of Organic Chemistry at the University of Manchester, where he and his research group work on the construction of molecules with defined shapes - in particular those where control of conformation and limitation of flexibility is important. Jonathan was awarded a BA (Natural Sciences) from Churchill College, Cambridge before completing his PhD with Stuart Warren, also at the University of Cambridge. He has been at the University of Manchester since 1994. ; Nick Greeves is the Director of Teaching and Learning in the Department of Chemistry at the University of Liverpool. Nick is a Cambridge graduate, obtaining his PhD there in 1986 for work on the stereoselective Horner-Wittig reaction with Stuart Warren. He then held a Harkness Fellowship at the University of Wisconsin-Madison and at Stanford University, California, and a Research Fellowship at Cambridge University before joining Liverpool in 1989 where he is currently a Senior Lecturer.; Stuart Warren i

Inhalt

1 What is organic chemistry?; 2 Organic structures; 3 Determining organic structures; 4 Structure of molecules; 5 Organic reactions; 6 Nucleophilic addition to the carbonyl group; 7 Delocalization and conjugation; 8 Acidity, basicity, and pKa; 9 Using organometallic reagents to make C-C bonds; 10 Nucleophilic substitution at the carbonyl group; 11 Nucleophilic substitution at C=O with loss of carbonyl oxygen; 12 Equilibria, rates and mechanisms; 13 1H NMR: Proton nuclear magnetic resonance; 14 Stereochemistry; 15 Nucleophilic substitution at saturated carbon; 16 Conformational analysis; 17 Elimination reactions; 18 Review of spectroscopic methods; 19 Electrophilic addition to alkenes; 20 Formation and reactions of enols and enolates; 21 Electrophilic aromatic substitution; 22 Conjugate addition and nucleophilic aromatic substitution; 23 Chemoselectivity and protecting groups; 24 Regioselectivity; 25 Alkylation of enolates; 26 Reactions of enolates with carbonyl compounds: the aldol and Claisen reactions; 27 Sulfur, silicon and phosphorus in organic chemistry; 28 Retrosynthetic analysis; 29 Aromatic heterocycles 1: structures and reactions; 30 Aromatic heterocycles 2: synthesis; 31 Saturated heterocycles and stereoelectronics; 32 Stereoselectivity in cyclic molecules; 33 Diastereoselectivity; 34 Pericyclic reactions 1: cycloadditions; 35 Pericyclic reactions 2: sigmatropic and electrocyclic reactions; 36 Participation, rearrangement and fragmentation; 37 Radical reactions; 38 Synthesis and reactions of carbenes; 39 Determining reaction mechanisms; 40 Organometallic chemistry; 41 Asymmetric synthesis; 42 Organic chemistry of life; 43 Organic chemistry today